Potentially malignant mucosal disease

This visual ‘atlas’ will help you to identify and describe non-malignant, potentially malignant and malignant oral lesions.

A diverse range of mucosal lesions can occur in the oral cavity. The history and clinical presentation of the non-malignant conditions listed below will help you differentiate them from potentially malignant or cancerous lesions. However, occasionally this can be difficult. If a lesion is suspicious, refer your patient for biopsy and definitive diagnosis.

The stage when oral cancer is diagnosed is important, as it indicates prognosis. Stage I and II oral cancer corresponds directly to size, with no evidence of metastases. Stage III and IV oral cancer has spread to the lymph nodes or distant organs. Detection of oral cancer at an early stage can save your patient’s life.

Potentially malignant mucosal disease

Leukoplakia

  • Homogenous leukoplakia
  • Non-homogenous leukoplakia
    • Verrucous leukoplakia
    • Nodular leukoplakia
    • Erythroleukoplakia

Oral lichen planus

  • Reticular oral lichen planus
  • Erythematous oral lichen planus
  • Ulcerative oral lichen planus
  • Plaque-like oral lichen planus
Last updated: January 2021